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[Remote] Senior AI Engineer, Real-World Data

Work from home Full-time role Hiring

Note: The job is a remote job and is open to candidates in USA. Natera is a global leader in cell-free DNA testing, focused on oncology, women's health, and organ health. They are seeking a Senior AI Engineer to design and build intelligent agent workflows that enhance the quality and efficiency of their Real-World Data clinical extraction platform.

Responsibilities

  • Design, build, and deploy agent-based AI systems that improve the quality and reliability of clinical data extraction in production
  • Own technical design and delivery for agent workflows
  • Integrate new AI capabilities into existing production platforms with attention to performance, scalability, and cost
  • Partner with clinical AI, engineering, and product teams to prioritize problems, define success metrics, and ship incremental improvements
  • Develop evaluation and monitoring approaches to measure impact, guide iteration, and support safe deployment in a regulated environment
  • Provide technical leadership through clear documentation, design decisions, and pragmatic tradeoffs across accuracy, cost, and delivery timelines

Skills

  • Bachelor's or Master's degree in Computer Science, Engineering, or a related technical field; an advanced degree or background in a clinical or life sciences discipline is a plus
  • 7+ years of software engineering experience, including substantial work on production systems at scale
  • 3+ years building and shipping AI/ML-powered applications in production, with hands-on experience in LLM-based systems and multi-step or agent-based LLM workflows — including orchestration, structured outputs, error handling, and integration with downstream systems
  • Strong hands-on expertise in Python and modern software engineering practices, including testing, code review, workflow orchestration, and agile delivery in large existing codebases
  • Experience designing and operating AI systems in cloud environments, with AWS strongly preferred; experience with CI/CD, observability, and production support is expected
  • Proven ability to work independently and deliver end-to-end - from technical design through integration and rollout - with strong communication and collaboration across technical and non-technical stakeholders
  • Experience with retrieval-based or document-centric AI systems is strongly preferred
  • Experience in healthcare, life sciences, or other regulated industries is strongly preferred

Benefits

  • Comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents
  • Natera employees and their immediate families receive free testing
  • Fertility care benefits
  • Pregnancy and baby bonding leave
  • 401k benefits
  • Commuter benefits
  • Generous employee referral program

Company Overview

  • Natera specializes in cell-free DNA testing to provide a more targeted interventions to oncology, women's health, and organ health. It was founded in 2004, and is headquartered in San Carlos, California, USA, with a workforce of 5001-10000 employees. Its website is https://www.natera.com/.
  • Company H1B Sponsorship

  • Natera has a track record of offering H1B sponsorships, with 6 in 2026, 90 in 2025, 72 in 2024, 37 in 2023, 71 in 2022, 64 in 2021, 40 in 2020. Please note that this does not guarantee sponsorship for this specific role.
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